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How a sperm and an egg fuse together has long been a mystery. New research by scientists in Austria provides tantalizing clues, showing fertilization works like a lock and key across the animal kingdom, from fish to people. "We discovered this mechanism that's really fundamental across all vertebrates as far as we can tell," said co-author Andrea Pauli at the Research Institute of Molecular Pathology in Vienna. The team found that three proteins on the sperm join to form a sort of key that unlocks the egg, allowing the sperm to attach. Their...
ORLANDO, Fla. (AP) — Midwife Jennie Joseph touched Husna Mixon's pregnant belly, turned to the 7-year-old boy in the room with them and asked: "Want to help me check the baby?" With his small hand on hers, Joseph used a fetal monitor to find a heartbeat. "I hear it!" he said. A quick, steady thumping filled the room. It was a full-circle moment for the midwife and patient, who first met when Mixon was an uninsured teenager seeking prenatal care halfway through her pregnancy with the little boy. Joseph has been on a decades-long mission to u...
A growing number of women said they've tried to end their pregnancies on their own by doing things like taking herbs, drinking alcohol or even hitting themselves in the belly, a new study suggests. Researchers surveyed reproductive-age women in the U.S. before and after the Supreme Court overturned Roe v. Wade in June 2022. The proportion who reported trying to end pregnancies by themselves rose from 2.4% to 3.3%. "A lot of people are taking things into their own hands," said Dr. Grace Ferguson, a Pittsburgh OB-GYN and abortion provider who...
Thousands of women in states with abortion bans and restrictions are receiving abortion pills in the mail from states that have laws protecting prescribers, a new report shows. Tuesday's release of the #WeCount survey shows about 8,000 women a month in states that severely restrict abortion or place limits on having one through telehealth were getting the pills by mail by the end of 2023, the first time a number has been put on how often the medical system workaround is being used. The research was conducted for the Society of Family Planning,...
NAMPA, Idaho (AP) — Waiting in a long post office line with the latest shipment of "abortion aftercare kits," Kimra Luna got a text. A woman who'd taken abortion pills three weeks earlier was worried about bleeding — and disclosing the cause to a doctor. "Bleeding doesn't mean you need to go in," Luna responded on the encrypted messaging app Signal. "Some people bleed on and off for a month." It was a typically busy afternoon for Luna, a doula and reproductive care activist in a state with some of the strictest abortion laws in the nation. Tho...
NEW YORK (AP) — According to Elon Musk, the first human received an implant from his computer-brain interface company Neuralink over the weekend. In a Monday post on X, the platform formerly known as Twitter, Musk said that the patient received the implant the day prior and was "recovering well." He added that "initial results show promising neuron spike detection." The billionaire, who co-founded Neuralink, did not provide additional details about the patient. When Neuralink announced in September that it would begin recruiting people, the c...
Gene therapy has allowed several children born with inherited deafness to hear. A small study published Wednesday documents significantly restored hearing in five of six kids treated in China. On Tuesday, the Children's Hospital of Philadelphia announced similar improvements in an 11-year-old boy treated there. And earlier this month, Chinese researchers published a study showing much the same in two other children. So far, the experimental therapies target only one rare condition. But scientists say similar treatments could someday help many m...
Regulators on Friday approved two gene therapies for sickle cell disease that doctors hope can cure the painful, inherited blood disorder that afflicts mostly Black people in the U.S. The Food and Drug Administration said the one-time treatments can be used for patients 12 and older with severe forms of the disease. One, made by Vertex Pharmaceuticals and CRISPR Therapeutics, is the first approved therapy based on CRISPR, the gene editing tool that won its inventors the Nobel Prize in 2020. The other is made by Bluebird Bio and works...
Scientists are setting out to collect genetic material from 500,000 people of African ancestry to create what they believe will be the world's largest database of genomic information from the population. The hope is to build a new "reference genome" — a template to compare to full sets of DNA from individuals — and better understand genetic variants that affect Black people. It could eventually translate into new medicines and diagnostic tests — and help reduce health disparities. The initiative was launched Wednesday by Meharry Medical Colle...
A few months after South Dakota banned abortion last year, April Matson drove more than nine hours to take a friend to a Colorado clinic to get the procedure. The trip brought back difficult memories of Matson's own abortion at the same clinic in 2016. The former grocery store worker and parent of two couldn't afford a hotel and slept in a tent near a horse pasture — bleeding and in pain. Getting an abortion has long been extremely difficult for Native Americans like Matson. It has become even tougher since the Supreme Court overturned Roe v...
Our Medieval ancestors left us with a biological legacy: Genes that may have helped them survive the Black Death make us more susceptible to certain diseases today. It's a prime example of the way germs shape us over time, scientists say in a new study published Wednesday in the journal Nature. "Our genome today is a reflection of our whole evolutionary history" as we adapt to different germs, said Luis Barreiro, a senior author of the research. Some, like those behind the bubonic plague, have had a big impact on our immune systems. The Black...
Researcher Dhruv Sareen's own stem cells are now orbiting the Earth. The mission? To test whether they'll grow better in zero gravity. Scientists at Cedars-Sinai Medical Center in Los Angeles are trying to find new ways to produce huge batches of a type of stem cell that can generate nearly any other type of cell in the body — and potentially be used to make treatments for many diseases. The cells arrived over the weekend at the International Space Station on a supply ship. "I don't think I would be able to pay whatever it costs now" to take a...
What do we know about the new omicron mutant? It's a descendent of the earlier super-contagious "stealth omicron" and has quickly gained ground in the United States. BA.2.12.1 was responsible for 29% of new COVID-19 infections nationally last week, according to data reported Tuesday by the U.S. Centers for Disease Control and Prevention. And it caused 58% of reported infections in the New York region. The variant has been detected in at least 13 other countries, but the U.S. has the highest levels of it so far. Scientists say it spreads even...
Scientists say they have finally assembled the full genetic blueprint for human life, adding the missing pieces to a puzzle nearly completed two decades ago. An international team described the first-ever sequencing of a complete human genome – the set of instructions to build and sustain a human being – in research published Thursday in the journal Science. The previous effort, celebrated across the world, was incomplete because DNA sequencing technologies of the day weren't able to read certain parts of it. Even after updates, it was missing...
With coronavirus cases rising in parts of Europe and Asia, scientists worry that an extra-contagious version of the omicron variant may soon push cases up in the United States too. Experts are also keeping their eyes on another mutant: a rare delta-omicron hybrid that they say doesn't pose much of a threat right now but shows how wily the coronavirus can be. The U.S. will likely see an uptick in cases caused by the omicron descendant BA.2 starting in the next few weeks, according to Dr. Eric Topol, head of Scripps Research Translational...
Holly Nover grew up trying to hide her stutter. "I was very self conscious," said the 40-year-old St. Johns, Florida mom, whose 10-year-old son Colton also has a speech impediment. "So I developed habits to switch my words so it wouldn't be noticed." For centuries, people have feared being judged for stuttering, a condition often misunderstood as a psychological problem caused by things like bad parenting or emotional trauma. But research presented at a science conference on Saturday explores its biological underpinnings: genetics and brain...
As the omicron coronavirus variant spreads in southern Africa and pops up in countries all around the world, scientists are anxiously watching a battle play out that could determine the future of the pandemic. Can the latest competitor to the world-dominating delta overthrow it? Some scientists, poring over data from South Africa and the United Kingdom, suggest omicron could emerge the victor. "It's still early days, but increasingly, data is starting to trickle in, suggesting that omicron is likely to outcompete delta in many, if not all,...
The U.S. public health system has been starved for decades and lacks the resources to confront the worst health crisis in a century. Marshaled against a virus that has sickened at least 2.6 million in the U.S., killed more than 126,000 people and cost tens of millions of jobs and $3 trillion in federal rescue money, state and local government health workers on the ground are sometimes paid so little, they qualify for public aid. They track the coronavirus on paper records shared via fax. Working seven-day weeks for months on end, they fear pay...
